Sequestration of synaptic proteins by alpha-synuclein aggregates leading to neurotoxicity is inhibited by small peptide

α-Synuclein (α-syn) is a major component of Lewy bodies found in synucleinopathies including Parkinson’s disease (PD) and Dementia with Lewy Bodies (DLB). Under the pathological conditions, α-syn tends to generate a diverse form of aggregates showing toxicity to neuronal cells and able to transmit a...

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Detalles Bibliográficos
Autores principales: Choi, Mal-Gi, Kim, Mi Jin, Kim, Do-Geun, Yu, Ri, Jang, You-Na, Oh, Won-Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880409/
https://www.ncbi.nlm.nih.gov/pubmed/29608598
http://dx.doi.org/10.1371/journal.pone.0195339

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880409/
https://www.ncbi.nlm.nih.gov/pubmed/29608598
http://dx.doi.org/10.1371/journal.pone.0195339

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