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Interaction of lecithin:cholesterol acyltransferase with lipid surfaces and apolipoprotein A-I-derived peptides

LCAT is an enzyme responsible for the formation of cholesteryl esters from unesterified cholesterol (UC) and phospholipid (PL) molecules in HDL particles. However, it is poorly understood how LCAT interacts with lipoproteins and how apoA-I activates it. Here we have studied the interactions between...

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Detalles Bibliográficos
Autores principales: Casteleijn, Marco G., Parkkila, Petteri, Viitala, Tapani, Koivuniemi, Artturi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880497/
https://www.ncbi.nlm.nih.gov/pubmed/29438987
http://dx.doi.org/10.1194/jlr.M082685