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Development of dihydrochalcone-functionalized gold nanoparticles for augmented antineoplastic activity

BACKGROUND: Phloridzin, an antidiabetic and antineoplastic agent usually found in fruit trees, is a dihydrochalcone constituent that has a clinical/pharmaceutical significance as a sodium-glucose linked transport 2 (SGLT2) inhibitor. While the aglycone metabolite of phloridzin, phloretin, displays a...

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Detalles Bibliográficos
Autores principales: Payne, Jason N, Badwaik, Vivek D, Waghwani, Hitesh K, Moolani, Harsh V, Tockstein, Sarah, Thompson, David H, Dakshinamurthy, Rajalingam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880570/
https://www.ncbi.nlm.nih.gov/pubmed/29636609
http://dx.doi.org/10.2147/IJN.S143506