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The Wnt-β-catenin signaling regulated MRTF-A transcription to activate migration-related genes in human breast cancer cells

MRTF-A is a transcriptional co-activator being critical for multiple processes including tissue fibrosis and cancer metastasis. The Rho-actin signaling stimulates the nuclear translocation and transcriptional activity of MRTF-A with little effect on the expression of MRTF-A gene. High expression of...

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Detalles Bibliográficos
Autores principales: He, Hongpeng, Du, Fu, He, Yongping, Wei, Zhaoqiang, Meng, Chao, Xu, Yuexin, Zhou, Hao, Wang, Nan, Luo, Xue-Gang, Ma, Wenjian, Zhang, Tong-Cun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880600/
https://www.ncbi.nlm.nih.gov/pubmed/29632640
http://dx.doi.org/10.18632/oncotarget.23961