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The Wnt-β-catenin signaling regulated MRTF-A transcription to activate migration-related genes in human breast cancer cells
MRTF-A is a transcriptional co-activator being critical for multiple processes including tissue fibrosis and cancer metastasis. The Rho-actin signaling stimulates the nuclear translocation and transcriptional activity of MRTF-A with little effect on the expression of MRTF-A gene. High expression of...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880600/ https://www.ncbi.nlm.nih.gov/pubmed/29632640 http://dx.doi.org/10.18632/oncotarget.23961 |