Analysis of the 9p21.3 sequence associated with coronary artery disease reveals a tendency for duplication in a CAD patient

Tandem segmental duplications (SDs) greater than 10 kb are widespread in complex genomes. They provide material for gene divergence and evolutionary adaptation, while formation of specific de novo SDs is a hallmark of cancer and some human diseases. Most SDs map to distinct genomic regions termed ‘d...

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Detalles Bibliográficos
Autores principales: Kouprina, Natalay, Liskovykh, Mikhail, Lee, Nicholas C.O., Noskov, Vladimir N., Waterfall, Joshua J., Walker, Robert L., Meltzer, Paul S., Topol, Eric J., Larionov, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880603/
https://www.ncbi.nlm.nih.gov/pubmed/29632643
http://dx.doi.org/10.18632/oncotarget.24567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880603/
https://www.ncbi.nlm.nih.gov/pubmed/29632643
http://dx.doi.org/10.18632/oncotarget.24567

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