Designer exosomes produced by implanted cells intracerebrally deliver therapeutic cargo for Parkinson’s disease treatment

Exosomes are cell-derived nanovesicles (50–150 nm), which mediate intercellular communication, and are candidate therapeutic agents. However, inefficiency of exosomal message transfer, such as mRNA, and lack of methods to create designer exosomes have hampered their development into therapeutic inte...

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Detalles Bibliográficos
Autores principales: Kojima, Ryosuke, Bojar, Daniel, Rizzi, Giorgio, Hamri, Ghislaine Charpin-El, El-Baba, Marie Daoud, Saxena, Pratik, Ausländer, Simon, Tan, Kelly R., Fussenegger, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880805/
https://www.ncbi.nlm.nih.gov/pubmed/29610454
http://dx.doi.org/10.1038/s41467-018-03733-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880805/
https://www.ncbi.nlm.nih.gov/pubmed/29610454
http://dx.doi.org/10.1038/s41467-018-03733-8

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