Small molecules promote CRISPR-Cpf1-mediated genome editing in human pluripotent stem cells

Human pluripotent stem cells (hPSCs) have potential applications in biological studies and regenerative medicine. However, precise genome editing in hPSCs remains time-consuming and labor-intensive. Here we demonstrate that the recently identified CRISPR-Cpf1 can be used to efficiently generate knoc...

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Detalles Bibliográficos
Autores principales: Ma, Xiaojie, Chen, Xi, Jin, Yan, Ge, Wenyan, Wang, Weiyun, Kong, Linghao, Ji, Junfang, Guo, Xing, Huang, Jun, Feng, Xin-Hua, Fu, Junfen, Zhu, Saiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880812/
https://www.ncbi.nlm.nih.gov/pubmed/29610531
http://dx.doi.org/10.1038/s41467-018-03760-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880812/
https://www.ncbi.nlm.nih.gov/pubmed/29610531
http://dx.doi.org/10.1038/s41467-018-03760-5

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