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Small molecules promote CRISPR-Cpf1-mediated genome editing in human pluripotent stem cells
Human pluripotent stem cells (hPSCs) have potential applications in biological studies and regenerative medicine. However, precise genome editing in hPSCs remains time-consuming and labor-intensive. Here we demonstrate that the recently identified CRISPR-Cpf1 can be used to efficiently generate knoc...
Autores principales: | Ma, Xiaojie, Chen, Xi, Jin, Yan, Ge, Wenyan, Wang, Weiyun, Kong, Linghao, Ji, Junfang, Guo, Xing, Huang, Jun, Feng, Xin-Hua, Fu, Junfen, Zhu, Saiyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880812/ https://www.ncbi.nlm.nih.gov/pubmed/29610531 http://dx.doi.org/10.1038/s41467-018-03760-5 |
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