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JTE-852, a novel spleen tyrosine kinase inhibitor, blocks antigen-induced allergic reactions in rats

Conventional clinical treatments for allergy management remain suboptimal; new, orally available medications that improve a wide range of allergic signs have been desired. We previously demonstrated that JTE-852, a novel spleen tyrosine kinase inhibitor, potently and simultaneously suppresses secret...

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Detalles Bibliográficos
Autores principales: KATO, Toshinobu, OHTA, Takeshi, IWASAKI, Hidenori, KOBAYASHI, Hatsue, MATSUO, Akira, HATA, Takahiro, MATSUSHITA, Mutsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880827/
https://www.ncbi.nlm.nih.gov/pubmed/29375080
http://dx.doi.org/10.1292/jvms.17-0659