Sumoylation Protects Against β-Synuclein Toxicity in Yeast

Aggregation of α-synuclein (αSyn) plays a central role in the pathogenesis of Parkinson’s disease (PD). The budding yeast Saccharomyces cerevisiae serves as reference cell to study the interplay between αSyn misfolding, cytotoxicity and post-translational modifications (PTMs). The synuclein family i...

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Detalles Bibliográficos
Autores principales: Popova, Blagovesta, Kleinknecht, Alexandra, Arendarski, Patricia, Mischke, Jasmin, Wang, Dan, Braus, Gerhard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880895/
https://www.ncbi.nlm.nih.gov/pubmed/29636661
http://dx.doi.org/10.3389/fnmol.2018.00094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880895/
https://www.ncbi.nlm.nih.gov/pubmed/29636661
http://dx.doi.org/10.3389/fnmol.2018.00094

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