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Dendritic Cell Migration Toward CCL21 Gradient Requires Functional Cx43

Dendritic cells (DCs) travel through lymphatic vessels to transport antigens and present them to T cells in lymph nodes. DCs move directionally toward lymphatics by virtue of their CCR7 and a CCL21 chemotactic gradient. We evaluated in vivo and in bone marrow-derived dendritic cells (BMDCs) whether...

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Detalles Bibliográficos
Autores principales: Ruez, Richard, Dubrot, Juan, Zoso, Alice, Bacchetta, Marc, Molica, Filippo, Hugues, Stéphanie, Kwak, Brenda R., Chanson, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880903/
https://www.ncbi.nlm.nih.gov/pubmed/29636699
http://dx.doi.org/10.3389/fphys.2018.00288