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Regulation of Brain-Derived Neurotrophic Factor and Growth Factor Signaling Pathways by Tyrosine Phosphatase Shp2 in the Retina: A Brief Review

SH2 domain-containing tyrosine phosphatase-2 (PTPN11 or Shp2) is a ubiquitously expressed protein that plays a key regulatory role in cell proliferation, differentiation and growth factor (GF) signaling. This enzyme is well expressed in various retinal neurons and has emerged as an important player...

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Detalles Bibliográficos
Autores principales: Abbasi, Mojdeh, Gupta, Vivek, Chitranshi, Nitin, You, Yuyi, Dheer, Yogita, Mirzaei, Mehdi, Graham, Stuart L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880906/
https://www.ncbi.nlm.nih.gov/pubmed/29636665
http://dx.doi.org/10.3389/fncel.2018.00085