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Elevated Level of CD4(+) T Cell Immune Activation in Acutely HIV-1-Infected Stage Associates With Increased IL-2 Production and Cycling Expression, and Subsequent CD4(+) T Cell Preservation

Persistent immune activation is a striking consequence of HIV-1 infection and a driving force of CD4(+) T cell depletion and AIDS events during chronic infection. High level of T cell immune activation associates with antiretroviral therapy (ART)-treated clinical outcomes in chronically HIV-1-infect...

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Detalles Bibliográficos
Autores principales: Xia, Huan, Jiang, Wei, Zhang, Xin, Qin, Ling, Su, Bin, Li, Zhen, Sun, Jianping, Zhang, Yonghong, Zhang, Tong, Lu, Xiaofan, Wu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880913/
https://www.ncbi.nlm.nih.gov/pubmed/29636753
http://dx.doi.org/10.3389/fimmu.2018.00616