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Nanobody-Based Biologics for Modulating Purinergic Signaling in Inflammation and Immunity
Adenosine triphosphate (ATP) and nicotinamide adenine dinucleotide (NAD(+)) are released as danger signals from cells during infection and sterile inflammation. In the extracellular compartment ATP is converted by CD39, CD73, and other ecto-enzymes into metabolites that modulate the activity of T ce...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880931/ https://www.ncbi.nlm.nih.gov/pubmed/29636685 http://dx.doi.org/10.3389/fphar.2018.00266 |