D-Arg(0)-Bradykinin-Arg-Arg, a Latent Vasoactive Bradykinin B(2) Receptor Agonist Metabolically Activated by Carboxypeptidases

We previously reported hypotensive and vasodilator effects from C-terminally extended bradykinin (BK) sequences that behave as B(2) receptor (B(2)R) agonists activated by vascular or plasma peptidases. D-Arg(0)-BK-Arg-Arg (r-BK-RR) is a novel prodrug peptide hypothetically activated by two catalytic...

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Detalles Bibliográficos
Autores principales: Bachelard, Hélène, Charest-Morin, Xavier, Marceau, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880945/
https://www.ncbi.nlm.nih.gov/pubmed/29636689
http://dx.doi.org/10.3389/fphar.2018.00273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880945/
https://www.ncbi.nlm.nih.gov/pubmed/29636689
http://dx.doi.org/10.3389/fphar.2018.00273

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