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D-Arg(0)-Bradykinin-Arg-Arg, a Latent Vasoactive Bradykinin B(2) Receptor Agonist Metabolically Activated by Carboxypeptidases
We previously reported hypotensive and vasodilator effects from C-terminally extended bradykinin (BK) sequences that behave as B(2) receptor (B(2)R) agonists activated by vascular or plasma peptidases. D-Arg(0)-BK-Arg-Arg (r-BK-RR) is a novel prodrug peptide hypothetically activated by two catalytic...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880945/ https://www.ncbi.nlm.nih.gov/pubmed/29636689 http://dx.doi.org/10.3389/fphar.2018.00273 |