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Topical Bixin Confers NRF2-Dependent Protection Against Photodamage and Hair Graying in Mouse Skin

Environmental exposure to solar ultraviolet (UV) radiation causes acute photodamage, premature aging, and skin cancer, attributable to UV-induced genotoxic, oxidative, and inflammatory stress. The transcription factor NRF2 [nuclear factor erythroid 2 (E2)-related factor 2] is the master regulator of...

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Detalles Bibliográficos
Autores principales: Rojo de la Vega, Montserrat, Zhang, Donna D., Wondrak, Georg T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880955/
https://www.ncbi.nlm.nih.gov/pubmed/29636694
http://dx.doi.org/10.3389/fphar.2018.00287