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Topical Bixin Confers NRF2-Dependent Protection Against Photodamage and Hair Graying in Mouse Skin
Environmental exposure to solar ultraviolet (UV) radiation causes acute photodamage, premature aging, and skin cancer, attributable to UV-induced genotoxic, oxidative, and inflammatory stress. The transcription factor NRF2 [nuclear factor erythroid 2 (E2)-related factor 2] is the master regulator of...
Autores principales: | Rojo de la Vega, Montserrat, Zhang, Donna D., Wondrak, Georg T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880955/ https://www.ncbi.nlm.nih.gov/pubmed/29636694 http://dx.doi.org/10.3389/fphar.2018.00287 |
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