TGFβ-facilitated optic fissure fusion and the role of bone morphogenetic protein antagonism

The optic fissure is a transient gap in the developing vertebrate eye, which must be closed as development proceeds. A persisting optic fissure, coloboma, is a major cause for blindness in children. Although many genes have been linked to coloboma, the process of optic fissure fusion is still little...

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Detalles Bibliográficos
Autores principales: Knickmeyer, Max D., Mateo, Juan L., Eckert, Priska, Roussa, Eleni, Rahhal, Belal, Zuniga, Aimee, Krieglstein, Kerstin, Wittbrodt, Joachim, Heermann, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881030/
https://www.ncbi.nlm.nih.gov/pubmed/29593116
http://dx.doi.org/10.1098/rsob.170134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881030/
https://www.ncbi.nlm.nih.gov/pubmed/29593116
http://dx.doi.org/10.1098/rsob.170134

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