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Identifying RNA splicing factors using IFT genes in Chlamydomonas reinhardtii

Intraflagellar transport moves proteins in and out of flagella/cilia and it is essential for the assembly of these organelles. Using whole-genome sequencing, we identified splice site mutations in two IFT genes, IFT81 (fla9) and IFT121 (ift121-2), which lead to flagellar assembly defects in the unic...

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Detalles Bibliográficos
Autores principales: Lin, Huawen, Zhang, Zhengyan, Iomini, Carlo, Dutcher, Susan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881031/
https://www.ncbi.nlm.nih.gov/pubmed/29514868
http://dx.doi.org/10.1098/rsob.170211