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The Establishment of a CSF-Contacting Nucleus “Knockout” Model Animal

To establish an entirely cerebrospinal fluid (CSF)-contacting nucleus-deficient model animal, we used cholera toxin B subunit (CB)- saporin (SAP), which is an analog of CB-HRP that specifically labels the CSF-contacting nucleus, to exclusively damage the nucleus. The effectiveness and specificity of...

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Detalles Bibliográficos
Autores principales: Song, Si-Yuan, Zhang, Li-Cai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881085/
https://www.ncbi.nlm.nih.gov/pubmed/29636668
http://dx.doi.org/10.3389/fnana.2018.00022