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OASL1 Traps Viral RNAs in Stress Granules to Promote Antiviral Responses

Oligoadenylate synthetase (OAS) protein family is the major interferon (IFN)-stimulated genes responsible for the activation of RNase L pathway upon viral infection. OAS-like (OASL) is also required for inhibition of viral growth in human cells, but the loss of one of its mouse homolog, OASL1, cause...

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Detalles Bibliográficos
Autores principales: Kang, Ji-Seon, Hwang, Yune-Sahng, Kim, Lark Kyun, Lee, Sujung, Lee, Wook-Bin, Kim-Ha, Jeongsil, Kim, Young-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881095/
https://www.ncbi.nlm.nih.gov/pubmed/29463066
http://dx.doi.org/10.14348/molcells.2018.2293