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13 reasons why the brain is susceptible to oxidative stress

The human brain consumes 20% of the total basal oxygen (O(2)) budget to support ATP intensive neuronal activity. Without sufficient O(2) to support ATP demands, neuronal activity fails, such that, even transient ischemia is neurodegenerative. While the essentiality of O(2) to brain function is clear...

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Detalles Bibliográficos
Autores principales: Cobley, James Nathan, Fiorello, Maria Luisa, Bailey, Damian Miles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881419/
https://www.ncbi.nlm.nih.gov/pubmed/29413961
http://dx.doi.org/10.1016/j.redox.2018.01.008