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13 reasons why the brain is susceptible to oxidative stress
The human brain consumes 20% of the total basal oxygen (O(2)) budget to support ATP intensive neuronal activity. Without sufficient O(2) to support ATP demands, neuronal activity fails, such that, even transient ischemia is neurodegenerative. While the essentiality of O(2) to brain function is clear...
Autores principales: | Cobley, James Nathan, Fiorello, Maria Luisa, Bailey, Damian Miles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881419/ https://www.ncbi.nlm.nih.gov/pubmed/29413961 http://dx.doi.org/10.1016/j.redox.2018.01.008 |
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