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Retinoid isomerase inhibitors impair but do not block mammalian cone photoreceptor function

Visual function in vertebrates critically depends on the continuous regeneration of visual pigments in rod and cone photoreceptors. RPE65 is a well-established retinoid isomerase in the pigment epithelium that regenerates rhodopsin during the rod visual cycle; however, its contribution to the regene...

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Detalles Bibliográficos
Autores principales: Kiser, Philip D., Zhang, Jianye, Sharma, Aditya, Angueyra, Juan M., Kolesnikov, Alexander V., Badiee, Mohsen, Tochtrop, Gregory P., Kinoshita, Junzo, Peachey, Neal S., Li, Wei, Kefalov, Vladimir J., Palczewski, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881442/
https://www.ncbi.nlm.nih.gov/pubmed/29500274
http://dx.doi.org/10.1085/jgp.201711815