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Retinoid isomerase inhibitors impair but do not block mammalian cone photoreceptor function
Visual function in vertebrates critically depends on the continuous regeneration of visual pigments in rod and cone photoreceptors. RPE65 is a well-established retinoid isomerase in the pigment epithelium that regenerates rhodopsin during the rod visual cycle; however, its contribution to the regene...
Autores principales: | Kiser, Philip D., Zhang, Jianye, Sharma, Aditya, Angueyra, Juan M., Kolesnikov, Alexander V., Badiee, Mohsen, Tochtrop, Gregory P., Kinoshita, Junzo, Peachey, Neal S., Li, Wei, Kefalov, Vladimir J., Palczewski, Krzysztof |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881442/ https://www.ncbi.nlm.nih.gov/pubmed/29500274 http://dx.doi.org/10.1085/jgp.201711815 |
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