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Calcium-induced release of calcium in muscle: 50 years of work and the emerging consensus
Ryanodine-sensitive intracellular Ca(2+) channels (RyRs) open upon binding Ca(2+) at cytosolic-facing sites. This results in concerted, self-reinforcing opening of RyRs clustered in specialized regions on the membranes of Ca(2+) storage organelles (endoplasmic reticulum and sarcoplasmic reticulum),...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Rockefeller University Press
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881447/ https://www.ncbi.nlm.nih.gov/pubmed/29514865 http://dx.doi.org/10.1085/jgp.201711959 |