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Regulation of amyloid-β dynamics and pathology by the circadian clock

Nighttime restlessness and daytime drowsiness are common and early symptoms of Alzheimer’s Disease (AD). This symptomology implicates dysfunctional biological timing, yet the role of the circadian system in AD pathogenesis is unknown. To evaluate the role of the circadian clock in amyloid-β (Aβ) dyn...

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Detalles Bibliográficos
Autores principales: Kress, Geraldine J., Liao, Fan, Dimitry, Julie, Cedeno, Michelle R., FitzGerald, Garret A., Holtzman, David M., Musiek, Erik S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881473/
https://www.ncbi.nlm.nih.gov/pubmed/29382695
http://dx.doi.org/10.1084/jem.20172347