Tom70 enhances mitochondrial preprotein import efficiency by binding to internal targeting sequences

The biogenesis of mitochondria depends on the import of hundreds of preproteins. N-terminal matrix-targeting signals (MTSs) direct preproteins to the surface receptors Tom20, Tom22, and Tom70. In this study, we show that many preproteins contain additional internal MTS-like signals (iMTS-Ls) in thei...

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Detalles Bibliográficos
Autores principales: Backes, Sandra, Hess, Steffen, Boos, Felix, Woellhaf, Michael W., Gödel, Sabrina, Jung, Martin, Mühlhaus, Timo, Herrmann, Johannes M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881500/
https://www.ncbi.nlm.nih.gov/pubmed/29382700
http://dx.doi.org/10.1083/jcb.201708044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881500/
https://www.ncbi.nlm.nih.gov/pubmed/29382700
http://dx.doi.org/10.1083/jcb.201708044

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