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Altered chemomechanical coupling causes impaired motility of the kinesin-4 motors KIF27 and KIF7

Kinesin-4 motors play important roles in cell division, microtubule organization, and signaling. Understanding how motors perform their functions requires an understanding of their mechanochemical and motility properties. We demonstrate that KIF27 can influence microtubule dynamics, suggesting a con...

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Detalles Bibliográficos
Autores principales: Yue, Yang, Blasius, T. Lynne, Zhang, Stephanie, Jariwala, Shashank, Walker, Benjamin, Grant, Barry J., Cochran, Jared C., Verhey, Kristen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881503/
https://www.ncbi.nlm.nih.gov/pubmed/29351996
http://dx.doi.org/10.1083/jcb.201708179