Single-molecule imaging reveals dynamic biphasic partition of RNA-binding proteins in stress granules

Stress granules (SGs) are cytosolic, nonmembranous RNA–protein complexes. In vitro experiments suggested that they are formed by liquid–liquid phase separation; however, their properties in mammalian cells remain unclear. We analyzed the distribution and dynamics of two paradigmatic RNA-binding prot...

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Detalles Bibliográficos
Autores principales: Niewidok, Benedikt, Igaev, Maxim, Pereira da Graca, Abel, Strassner, Andre, Lenzen, Christine, Richter, Christian P., Piehler, Jacob, Kurre, Rainer, Brandt, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881506/
https://www.ncbi.nlm.nih.gov/pubmed/29463567
http://dx.doi.org/10.1083/jcb.201709007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881506/
https://www.ncbi.nlm.nih.gov/pubmed/29463567
http://dx.doi.org/10.1083/jcb.201709007

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