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Visualizing transcription factor dynamics in living cells

The assembly of sequence-specific enhancer-binding transcription factors (TFs) at cis-regulatory elements in the genome has long been regarded as the fundamental mechanism driving cell type–specific gene expression. However, despite extensive biochemical, genetic, and genomic studies in the past thr...

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Detalles Bibliográficos
Autores principales: Liu, Zhe, Tjian, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881510/
https://www.ncbi.nlm.nih.gov/pubmed/29378780
http://dx.doi.org/10.1083/jcb.201710038