A small‐molecule PAI‐1 inhibitor prevents bone loss by stimulating bone formation in a murine estrogen deficiency‐induced osteoporosis model

Osteoporosis is a progressive bone disease caused by an imbalance between bone resorption and formation. Recently, plasminogen activator inhibitor‐1 (PAI‐1) was shown to play an important role in bone metabolism using PAI‐1‐deficient mice. In this study, we evaluated the therapeutic benefits of nove...

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Detalles Bibliográficos
Autores principales: Jin, Guangwen, Aobulikasimu, Alkebaier, Piao, Jinying, Aibibula, Zulipiya, Koga, Daisuke, Sato, Shingo, Ochi, Hiroki, Tsuji, Kunikazu, Nakabayashi, Tetsuo, Miyata, Toshio, Okawa, Atsushi, Asou, Yoshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881535/
https://www.ncbi.nlm.nih.gov/pubmed/29632806
http://dx.doi.org/10.1002/2211-5463.12390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881535/
https://www.ncbi.nlm.nih.gov/pubmed/29632806
http://dx.doi.org/10.1002/2211-5463.12390

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