Two distinct conformational states define the interaction of human RAD51‐ATP with single‐stranded DNA

An essential mechanism for repairing DNA double‐strand breaks is homologous recombination (HR). One of its core catalysts is human RAD51 (hRAD51), which assembles as a helical nucleoprotein filament on single‐stranded DNA, promoting DNA‐strand exchange. Here, we study the interaction of hRAD51 with...

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Detalles Bibliográficos
Autores principales: Brouwer, Ineke, Moschetti, Tommaso, Candelli, Andrea, Garcin, Edwige B, Modesti, Mauro, Pellegrini, Luca, Wuite, Gijs JL, Peterman, Erwin JG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881629/
https://www.ncbi.nlm.nih.gov/pubmed/29507080
http://dx.doi.org/10.15252/embj.201798162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881629/
https://www.ncbi.nlm.nih.gov/pubmed/29507080
http://dx.doi.org/10.15252/embj.201798162

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