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Transcriptomic and proteomic analysis of potential therapeutic target genes in the liver of metformin-treated Sprague-Dawley rats with type 2 diabetes mellitus

The main actions of metformin are as follows: To reduce hyperglycemia via the suppression of gluconeogenesis, improve glucose uptake and insulin sensitivity, and stimulate activation of adenosine monophosphate-activated protein kinase during the treatment of diabetes mellitus. It is well known that...

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Detalles Bibliográficos
Autores principales: Chen, Yitao, Wu, Yangsheng, Yang, Yuanxiao, Xu, Zhiwei, Tong, Junfeng, Li, Zheming, Zhou, Xiaojie, Li, Changyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881648/
https://www.ncbi.nlm.nih.gov/pubmed/29512687
http://dx.doi.org/10.3892/ijmm.2018.3535