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Transcriptomic and proteomic analysis of potential therapeutic target genes in the liver of metformin-treated Sprague-Dawley rats with type 2 diabetes mellitus
The main actions of metformin are as follows: To reduce hyperglycemia via the suppression of gluconeogenesis, improve glucose uptake and insulin sensitivity, and stimulate activation of adenosine monophosphate-activated protein kinase during the treatment of diabetes mellitus. It is well known that...
Autores principales: | Chen, Yitao, Wu, Yangsheng, Yang, Yuanxiao, Xu, Zhiwei, Tong, Junfeng, Li, Zheming, Zhou, Xiaojie, Li, Changyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881648/ https://www.ncbi.nlm.nih.gov/pubmed/29512687 http://dx.doi.org/10.3892/ijmm.2018.3535 |
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