MCMV triggers ROS/NLRP3-associated inflammasome activation in the inner ear of mice and cultured spiral ganglion neurons, contributing to sensorineural hearing loss

Congenital cytomegalovirus (CMV) infection is the most common infectious cause of sensorineural hearing loss in children. While the importance of CMV-induced SNHL has been described, the mechanisms underlying its pathogenesis and the role of inflammatory responses remain elusive. The present study e...

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Detalles Bibliográficos
Autores principales: Zhuang, Wei, Wang, Caiji, Shi, Xi, Qiu, Shiwei, Zhang, Shili, Xu, Bing, Chen, Min, Jiang, Wen, Dong, Hongyan, Qiao, Yuehua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881649/
https://www.ncbi.nlm.nih.gov/pubmed/29512778
http://dx.doi.org/10.3892/ijmm.2018.3539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881649/
https://www.ncbi.nlm.nih.gov/pubmed/29512778
http://dx.doi.org/10.3892/ijmm.2018.3539

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