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Benzimidazoles Promote Anti-TNF Mediated Induction of Regulatory Macrophages and Enhance Therapeutic Efficacy in a Murine Model

BACKGROUND AND AIMS: Regulatory macrophages play a critical role in tissue repair, and we have previously shown that anti-tumour necrosis factor [TNF] antibodies induce these macrophages in vitro and in vivo in IBD patients. The induction of regulatory macrophages can be potentiated using the combin...

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Detalles Bibliográficos
Autores principales: Wildenberg, Manon E, Levin, Alon D, Ceroni, Alessandro, Guo, Zhen, Koelink, Pim J, Hakvoort, Theodorus B M, Westera, Liset, Bloemendaal, Felicia M, Brandse, Johannan F, Simmons, Alison, D’Haens, Geert R, Ebner, Daniel, van den Brink, Gijs R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881671/
https://www.ncbi.nlm.nih.gov/pubmed/28961920
http://dx.doi.org/10.1093/ecco-jcc/jjx104