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Benzimidazoles Promote Anti-TNF Mediated Induction of Regulatory Macrophages and Enhance Therapeutic Efficacy in a Murine Model
BACKGROUND AND AIMS: Regulatory macrophages play a critical role in tissue repair, and we have previously shown that anti-tumour necrosis factor [TNF] antibodies induce these macrophages in vitro and in vivo in IBD patients. The induction of regulatory macrophages can be potentiated using the combin...
Autores principales: | Wildenberg, Manon E, Levin, Alon D, Ceroni, Alessandro, Guo, Zhen, Koelink, Pim J, Hakvoort, Theodorus B M, Westera, Liset, Bloemendaal, Felicia M, Brandse, Johannan F, Simmons, Alison, D’Haens, Geert R, Ebner, Daniel, van den Brink, Gijs R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881671/ https://www.ncbi.nlm.nih.gov/pubmed/28961920 http://dx.doi.org/10.1093/ecco-jcc/jjx104 |
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