Trifluoperazine induces apoptosis through the upregulation of Bax/Bcl-2 and downregulated phosphorylation of AKT in mesangial cells and improves renal function in lupus nephritis mice

The inhibition of mesangial cell (MC) proliferation has become an important therapy in preventing glomerular proliferation diseases. Trifluoperazine (TFP) has been reported to inhibit the proliferation of several types of cancer cell, however, the effects of TFP in renal proliferation diseases remai...

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Detalles Bibliográficos
Autores principales: Wang, Baodong, Luo, Yankun, Zhou, Xiaoshuang, Li, Rongshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881739/
https://www.ncbi.nlm.nih.gov/pubmed/29568865
http://dx.doi.org/10.3892/ijmm.2018.3562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881739/
https://www.ncbi.nlm.nih.gov/pubmed/29568865
http://dx.doi.org/10.3892/ijmm.2018.3562

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