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c-Myc regulates the CDK1/cyclin B1 dependent-G(2)/M cell cycle progression by histone H4 acetylation in Raji cells

Overexpression of c-Myc is involved in the tumorigenesis of B-lineage acute lymphoblastic leukemia (B-ALL), but the mechanism is not well understood. In the present study, a c-Myc-knockdown model (Raji-KD) was established using Raji cells, and it was indicated that c-Myc regulates the expression of...

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Detalles Bibliográficos
Autores principales: Yang, Yan, Xue, Kai, Li, Zhi, Zheng, Wei, Dong, Weijie, Song, Jiazhe, Sun, Shijie, Ma, Tonghui, Li, Wenzhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881754/
https://www.ncbi.nlm.nih.gov/pubmed/29512702
http://dx.doi.org/10.3892/ijmm.2018.3519