Overexpression of adrenomedullin protects mesenchymal stem cells against hypoxia and serum deprivation-induced apoptosis via the Akt/GSK3β and Bcl-2 signaling pathways

The poor survival rate of transplanted mesenchymal stem cells (MSCs) within the ischemic heart limits their therapeutic potential for cardiac repair. Adrenomedullin (ADM) has been identified as a potent apoptotic inhibitor. The present study aimed to investigate the protective effects of ADM on MSCs...

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Detalles Bibliográficos
Autores principales: Si, Hongjin, Zhang, Yao, Song, Yuqing, Li, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881801/
https://www.ncbi.nlm.nih.gov/pubmed/29512737
http://dx.doi.org/10.3892/ijmm.2018.3533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881801/
https://www.ncbi.nlm.nih.gov/pubmed/29512737
http://dx.doi.org/10.3892/ijmm.2018.3533

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