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Mangiferin induces islet regeneration in aged mice through regulating p16(INK4a)

Previous studies by our group on mangiferin demonstrated that it exerts an antihyperglycemic effect through the regulation of cell cycle proteins in 3-month-old, partially pancreatectomized (PPx) mice. However, β-cell proliferation is known to become severely restricted with advanced age. Therefore,...

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Detalles Bibliográficos
Autores principales: Wang, Hailian, He, Xia, Lei, Tiantian, Liu, Yilong, Huai, Guoli, Sun, Minghan, Deng, Shaoping, Yang, Hongji, Tong, Rongsheng, Wang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881804/
https://www.ncbi.nlm.nih.gov/pubmed/29512742
http://dx.doi.org/10.3892/ijmm.2018.3524