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Valproic acid prevents glucocorticoid-induced osteonecrosis of the femoral head of rats

Glucocorticoids (GCs) are the most common cause of atraumatic osteonecrosis of the femoral head (ONFH) because their effect compromises the osteogenic capability of bone marrow-derived mesenchymal stem cells (BMSCs). Valproic acid (VPA) is a widely used anti-epileptic and anticonvulsant drug. Previo...

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Detalles Bibliográficos
Autores principales: Zhou, Ding, Chen, Yi-Xuan, Yin, Jun-Hui, Tao, Shi-Cong, Guo, Shang-Chun, Wei, Zhan-Ying, Feng, Yong, Zhang, Chang-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881807/
https://www.ncbi.nlm.nih.gov/pubmed/29512684
http://dx.doi.org/10.3892/ijmm.2018.3534