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Peripheral nerve injury increases contribution of L-type calcium channels to synaptic transmission in spinal lamina II: Role of α2δ–1 subunits
BACKGROUND: Following peripheral nerve chronic constriction injury, the accumulation of the α2δ–1 auxiliary subunit of voltage-gated Ca(2+) channels in primary afferent terminals contributes to the onset of neuropathic pain. Overexpression of α2δ–1 in Xenopus oocytes increases the opening properties...
Autores principales: | Alles, Sascha RA, Garcia, Esperanza, Balasubramanyan, Sridhar, Jones, Karen, Tyson, John R, Joy, Twinkle, Snutch, Terrance P, Smith, Peter A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882044/ https://www.ncbi.nlm.nih.gov/pubmed/29580153 http://dx.doi.org/10.1177/1744806918765806 |
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