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Different effects of two mutations on the infectivity of Ebola virus glycoprotein in nine mammalian species

Ebola virus (EBOV), which belongs to the genus Ebolavirus, causes a severe and often fatal infection in primates, including humans, whereas Reston virus (RESTV) only causes lethal disease in non-human primates. Two amino acids (aa) at positions 82 and 544 of the EBOV glycoprotein (GP) are involved i...

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Detalles Bibliográficos
Autores principales: Kurosaki, Yohei, Ueda, Mahoko Takahashi, Nakano, Yusuke, Yasuda, Jiro, Koyanagi, Yoshio, Sato, Kei, Nakagawa, So
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882082/
https://www.ncbi.nlm.nih.gov/pubmed/29300152
http://dx.doi.org/10.1099/jgv.0.000999