Streptomyces coelicolor strains lacking polyprenol phosphate mannose synthase and protein O-mannosyl transferase are hyper-susceptible to multiple antibiotics

Polyprenol phosphate mannose (PPM) is a lipid-linked sugar donor used by extra-cytoplasmic glycosyl tranferases in bacteria. PPM is synthesiszed by polyprenol phosphate mannose synthase, Ppm1, and in most Actinobacteria is used as the sugar donor for protein O-mannosyl transferase, Pmt, in protein g...

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Detalles Bibliográficos
Autores principales: Howlett, Robert, Read, Nicholas, Varghese, Anpu, Kershaw, Charles, Hancock, Y., Smith, Margaret C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882110/
https://www.ncbi.nlm.nih.gov/pubmed/29458553
http://dx.doi.org/10.1099/mic.0.000605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882110/
https://www.ncbi.nlm.nih.gov/pubmed/29458553
http://dx.doi.org/10.1099/mic.0.000605

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