Neural retina-specific Aldh1a1 controls dorsal choroidal vascular development via Sox9 expression in retinal pigment epithelial cells

VEGF secreted from retinal pigment epithelial (RPE) cells is responsible for the choroidal vascular development; however, the molecular regulatory mechanism is unclear. We found that Aldh1a1(–/–) mice showed choroidal hypoplasia with insufficient vascularization in the dorsal region, although Aldh1a...

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Detalles Bibliográficos
Autores principales: Goto, So, Onishi, Akishi, Misaki, Kazuyo, Yonemura, Shigenobu, Sugita, Sunao, Ito, Hiromi, Ohigashi, Yoko, Ema, Masatsugu, Sakaguchi, Hirokazu, Nishida, Kohji, Takahashi, Masayo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882243/
https://www.ncbi.nlm.nih.gov/pubmed/29609731
http://dx.doi.org/10.7554/eLife.32358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882243/
https://www.ncbi.nlm.nih.gov/pubmed/29609731
http://dx.doi.org/10.7554/eLife.32358

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