Anticancer effect of (S)-crizotinib on osteosarcoma cells by targeting MTH1 and activating reactive oxygen species

MTH1 has become a new rising star in the field of ‘cancer phenotypic lethality’ and can be targeted in many kinds of tumors. This study aimed to explore the anticancer effect of MTH1-targeted drug (S)-crizotinib on osteosarcoma (OS) cells. We detected MTH1 expression in OS tissues and cells using im...

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Detalles Bibliográficos
Autores principales: Qing, Xiangcheng, Shao, Zengwu, Lv, Xiao, Pu, Feifei, Gao, Feng, Liu, Lei, Shi, Deyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Preclinical Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882294/
https://www.ncbi.nlm.nih.gov/pubmed/29420337
http://dx.doi.org/10.1097/CAD.0000000000000602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882294/
https://www.ncbi.nlm.nih.gov/pubmed/29420337
http://dx.doi.org/10.1097/CAD.0000000000000602

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