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Anticancer effect of (S)-crizotinib on osteosarcoma cells by targeting MTH1 and activating reactive oxygen species

MTH1 has become a new rising star in the field of ‘cancer phenotypic lethality’ and can be targeted in many kinds of tumors. This study aimed to explore the anticancer effect of MTH1-targeted drug (S)-crizotinib on osteosarcoma (OS) cells. We detected MTH1 expression in OS tissues and cells using im...

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Detalles Bibliográficos
Autores principales:	Qing, Xiangcheng, Shao, Zengwu, Lv, Xiao, Pu, Feifei, Gao, Feng, Liu, Lei, Shi, Deyao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2018
Materias:	Preclinical Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882294/ https://www.ncbi.nlm.nih.gov/pubmed/29420337 http://dx.doi.org/10.1097/CAD.0000000000000602

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